GENEVA: The World Health Organization (WHO) has issued a fresh advisory warning that symptoms associated with the newly detected COVID-19 variant, designated as PJ.2.1, closely resemble those of the common cold and seasonal influenza. The global health agency emphasized that infections cannot be identified through symptoms alone and require formal diagnostic testing for accurate detection.
According to the WHO, diagnostic testing remains the most reliable method for identifying the specific viral infection, which is crucial for determining appropriate medical treatments and public health measures. The organization confirmed that it is actively tracking the geographical spread of the emerging variant across multiple countries.
Meanwhile, Russian infectious disease specialist and virologist Elena Malinnikova noted that the PJ.2.1 variant may cause severe sore throat and prolonged post-recovery fatigue compared to previous strains.
First detected in Ontario, Canada in May 2026, the PJ.2.1 variant has since been identified in several countries, including the United States, Singapore, Australia, New Zealand, Israel, France, and Spain. In the US, wastewater surveillance indicates that PJ.2.1 is currently among the fastest-growing variants. Scientists are closely monitoring the lineage due to significant mutations in its spike protein, which facilitates the virus’s entry into human cells.
Classified as a descendant of the JN.1 lineage under the Omicron umbrella, laboratory evaluations indicate that PJ.2.1 possesses an enhanced binding affinity to the human ACE2 receptor. However, health experts emphasize that higher transmissibility does not necessarily equate to increased disease severity. Preliminary findings suggest there is currently no evidence indicating that PJ.2.1 causes more severe illness or possesses a significantly higher capacity to evade vaccine-induced immunity.
Health authorities recommend that individuals experiencing respiratory symptoms undergo diagnostic testing, maintain updated vaccination status, and follow official public health guidance to prevent potential surges.
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